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Submitted: 10 Jun 2025
Revision: 09 Dec 2025
Accepted: 28 Dec 2025
ePublished: 29 Jun 2026
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Avicenna J Clin Microbiol Infect. 2026;13(2): 111-118.
doi: 10.34172/ajcmi.3707
  Abstract View: 6
  PDF Download: 6

Original Article

Tracing Norovirus and Escherichia coli O157:H7 Contaminations in Green Leafy Vegetables in Iran: A Public Health Concern

Seyed Hani Mirzadeh 1 ORCID logo, Mojtaba Khosravi 2,3* ORCID logo, Hamidreza Kazemeini 1 ORCID logo, Rahem Khoshbakht 2,3 ORCID logo

1 Department of Food Hygiene, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran
2 Department of Pathobiology, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran
3 Zoonotic Diseases Research Group, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran
*Corresponding Author: Mojtaba Khosravi, Email: m.khosravi@ausmt.ac.ir, Email: mojtaba.kh.dvm@gmail.com

Abstract

Introduction: Vegetables contain many vital micronutrients, including vitamins and minerals, and are an important component of a healthy diet. However, they may be contaminated by pathogens present in contaminated soil, and water. Furthermore, the consumption of raw or insufficiently processed food pathogens, contaminated soil facilitates the transmission of enteric pathogens such as norovirus and Escherichia coli O157:H7 to humans.

Methods: This study aimed to assess the presence of human norovirus (HuNoV) genotypes I (GI) and II (GII), as well as E. coli O157:H7, in green leafy vegetables. Between December 2023 and June 2024, a total of 152 samples, including 38 lettuce, 38 watercress, 38 coriander, and 38 oregano, were collected from markets and farm gardens in the cities of Babol and Amol, located in Mazandaran Province. The reverse transcriptase polymerase chain reaction (RT-PCR) and conventional PCR were used to detect the targeted pathogens.

Results: The results revealed that 17 of 152 samples (11.18%; 95% CI: 6.65–17.30%) were positive for at least one of the target pathogens. Moreover, the contamination rates for HuNoV GI and GII were 1.97% (3/152) and 2.63% (4/152), respectively. E. coli O157:H7 was found in 6.58% (10/152) of the samples. Notably, the most positive samples were collected from farm-sourced vegetables. In addition, watercress exhibited the highest contamination rates for HuNoV GI (7.90%), HuNoV GII (2.63%), and E. coli O157:H7 (10.53%).

Conclusion: The results highlight the presence of several dangerous human enteric pathogens in leafy green vegetables. Considering the fecal-oral transmission route of these pathogens, their potential public health impact is substantial. Furthermore, the establishment of continuous, standardized surveillance systems is required to better understand environmental risk factors and to reduce contamination risks along the food supply chain.



Please cite this article as follows: Mirzadeh SH, Khosravi M, Kazemeini H, Khoshbakht R. Tracing norovirus and Escherichia coli O157:H7 contaminations in green leafy vegetables in iran: a public health concern. Avicenna J Clin Microbiol Infect 2026;13(2):111-118. doi:10.34172/ajcmi.3707
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