Hamadan University of Medical Sciences Avicenna Journal of Clinical Microbiology and Infection 2383-0298 2 2 2015 05 01 Bacterial and Viral Infections Among Hospitalized Injection Drug Users in Hamadan, Iran 25660 25660 10.17795/ajcmi-25660 EN Seyyed Hamid Hashemi Mojgan Mamani Fatemeh Esna Ashari Nazanin Sadat Faghih Journal Article 10.17795/ajcmi-25660 2014 11 28 2015 02 14 Background: Infectious complications among Injection Drug Users (IDUs) are associated with significant morbidity and mortality and place an enormous burden on the healthcare system. Objectives: The present study aimed to describe the clinical and epidemiological characteristics of infectious complications in a sample of IDUs admitted to a hospital in Hamadan, Iran. Patients and Methods: In a retrospective manner, medical records of IDUs admitted to an infectious diseases ward between 2007 and 2012 were reviewed. Data on patients’ demographic characteristics, reasons for admission, antibiotic treatment prior to admission, duration of hospital stay, mortality, and also the status of infection with hepatitis B, C, and HIV were recorded. Results: Data for 100 IDUs lead to 115 admission episodes were available during the study. Bacterial infections accounted for 71% of all admissions. Among bacterial infections, skin and soft tissue infections, endocarditis, bone and joined infections emerged as the most common types. For 29% of cases, the reason for admission was due to viral pathogens, among which HIV/AIDS was the most common. The prevalence rates for hepatitis B, hepatitis C and HIV infection were 10.0%, 6.0% and 23.0%, respectively. The mean duration of hospital stay was 15.1 ± 0.9 days (range: 8 - 45 days). During the study period, 13 deaths were documented. Conclusions: Despite implementation of community-level harm reduction strategies in Iran, infectious complications due to illicit drug use are frequent and often require care at the hospital. Introducing harm reductions services at an inpatient level may improve the quality of care provided and help reduce the burden of accrue from drug use.