Hamadan University of Medical Sciences Avicenna Journal of Clinical Microbiology and Infection 2383-0298 7 4 2020 12 31 Clinical Effectiveness of Ertapenem Versus Piperacillin/Tazobactam in Patients With Mild to Moderate Intraabdominal Infections: A Systematic Review and Metaanalysis of Randomized Controlled Trials 129 134 10.34172/ajcmi.2020.28 EN Mehran Pezeshki https://orcid.org/0000-0001-8970-7923 Fatemeh Soleymani Meysam Seyedifar REVIEW 10.34172/ajcmi.2020.28 2020 12 01 2020 12 13 Purpose: This study aimed to search for randomized clinical trials evaluating the clinical effectiveness of ertapenem compared to piperacillin/tazob actam in adult patients with mild to moderate intra-abdominal infections. Results: The analysis of 4 studies involving 767 patients in the ertapenem group and 728 patients in the piperacillin/tazobactam group showed that ertapenem can be 3% more effective than piperacillin/tazobactam (Weighted mean differences = 3.02, confidence interval (0.79-6.84) although the difference was insignificant (I-squared = 0.0%, P=0.98)