Submitted: 01 Nov 2020
Accepted: 02 Dec 2019
ePublished: 31 Dec 2019
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Avicenna J Clin Microbiol Infect. 2019;6(4): 133-137.
doi: 10.34172/ajcmi.2019.24
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Review Article

Microscopy and its Application in Microbiology and Medicine From Light to Quantum Microscopy: A Mini Review

Amir Khodavirdipour 1,2* ORCID logo, Mahboobeh Mehregan 3, Ali Rajabi 2, Yasoub Shiri 4

1 Division of Human Genetics, Department of Anatomy, St. John’s Hospital, Bangalore, India
2 Department of Biology, Faculty of Natural sciences, University of Tabriz, Tabriz, Tabriz, Iran
3 Department of Biology, Faculty of Science, University of Zabol, Zabol, Iran
4 Assistant Professor of Agronomy and Plant Breeding, Agricultural Research Institute, University of Zabol, Zabol, Iran
*Corresponding Author: *Corresponding author: Amir Khodavirdipour Division of Human Genetics, Department of Anatomy, St. John’s Hospital, Bangalore, Karnataka, INDIA Tel: 0091-9986695070, Email: , Email: amir_kvp@yahoo.com


The invention of the microscope was a great help to science to reach a new extension, especially biology. By employing microscopes, the researchers were able to prove new dimensions of living such as a microorganism, work, and cell study, and go in-depth of the minute part of fungi, plants or even the animals. In the mid-20th century, the electron was a great help and opened a new horizon. The scanning microscopes are even more delicate and sophisticated and also have higher magnification power compared to light microscopes. Basically, microscopes utilize the simply visible rays which refract the lenses, X-rays, electron, and infrared rays. In addition, they are designed to detect smaller and smaller particles and structures. Further, scanning electron microscopes are capable of resolving viruses which are extremely smaller than any microorganism and cell, they can enlarge the view of small viruses, which allows the researcher and scientists to develop the cure or a new vaccine for related diseases in animals or even humans. Furthermore, scanning electron microscopes have the power of magnification even till million times, almost molecule size, viruses and also nanoparticles. Moreover, they use software for correcting and enhancing the magnification and resolution of the image. The software helps to view the desired objects even if they are a few molecules thick. This mini-review extensively discusses each type and their different available classifications.
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