Seyyed Hamid Hashemi
1* 
, Mahmoud Farshchian
2, Hamidreza Ghasemi Basir
3, Maria Shirvani
41 Department of Infectious Diseases, Hamadan University of Medical Sciences, Hamadan, Iran
2 Department of Dermatology, Hamadan University of Medical Sciences, Hamadan, Iran
3 Department of Pathlogy, Hamadan University of Medical Sciences, Hamadan, Iran
4 Department of Infectious Diseases, Kermanshah University of Medical Sciences, Kermanshah, Iran
*Corresponding Author: Corresponding author: Dr. Seyyed Hamid Hashemi, Division of Infectious Diseases, Sina Hospital, Mirzadeh-Eshghi St, Hamadan, Iran. Tel: +98-8138274192, Fax: +98-8138276010, Email:
shahashemi@yahoo.com
Abstract
Erythema induratum of bazin (EIB) is a hypersensitivity reaction to Mycobacterium tuberculosis infection. The diagnosis can be difficult because tubercle bacilli are usually not found in smears or cultures of lesions. This study reports on a case of EIB in a 13-year-old female, who presented multiple tender nodules on her lower extremities. Biopsy of the nodule revealed histopathologic changes compatible with erythema induratum. QuantiFERON test was positive. The patient received a 6-month duration of anti-tuberculosis treatment. The lesions disappeared during therapy, and no pigmentation was observed at the end of treatment. After a year of follow up, there was no recurrence of the disease.