Submitted: 12 Jul 2018
Accepted: 05 Aug 2018
ePublished: 27 Aug 2018
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)

Avicenna J Clin Microbiol Infect. 2018;5(3): 67-70.
doi: 10.34172/ajcmi.2018.13
  Abstract View: 808
  PDF Download: 583

Original Article

Characterization of Staphylococcus aureus Isolated From Wound Infectious in Diabetes Clinic of Hazrat Fatemeh Zahra (SA) Hospital

Vajiheh Nourbakhsh 1 ORCID logo, Fahimeh Nourbakhsh 2* ORCID logo, Elaheh Tajbakhsh 3, Samaneh Borooni 4, Dana Daneshmand 5

1 Hazrat Fatemeh Zahra (SA) Hospital, Depending on the Treatment and Management of Social Security in Isfahan, Isfahan, Iran
2 Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
3 Department of Microbiology, Faculty of Basic Science, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
4 Nourdanesh Institute of Higher Education of Meymeh, Isfahan, Iran
5 Nosocomial Infection Research Center, Isfahan University of Medical Science, Isfahan, Iran
*Corresponding Author: *Corresponding author: Fahimeh Nourbakhsh, Ph.D. Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, P. O. Box, 1365-91775, I.R. Iran. Phone: +98-51-3180-1176 Email:, Email: Nourbakhsh951@mums.ac.ir


Background: Staphylococcus aureus is a gram positive pathogen which causes a wide range of infections. The present study aimed to investigate genotypic and phenotypic screening about biofilm formation in S. aureus isolated from wound infections in a diabetes clinic in Hazrat Fatemeh Zahra (SA) hospital.

Methods: A total of 267 clinical samples were collected from various types of wound infections in the diabetes clinic of Hazrat Fatemeh Zahra (SA) hospital, Isfahan, Iran. The methicillin-resistant S. aureus (MRSA) isolates were selected and biofilm formation and its related genes were analyzed by polymerase chain reaction (PCR).

Results: The results showed that 95 out of 132 samples were MRSA. The high resistance was seen to methicillin, erythromycin, ciprofloxacin, and penicillin. Phenotypic results showed that 48.3% of the isolates were high biofilm producers, 29.1% were average biofilm producers, and 10.6% were low biofilm producers.

Conclusions: According to the results of this study, the expression levels of biofilm-associated genes significantly increased, and high prevalence of antibiotic resistance was one of the important reasons for the development of drug resistance in patients.

First Name
Last Name
Email Address
Security code

Abstract View: 808

Your browser does not support the canvas element.

PDF Download: 583

Your browser does not support the canvas element.