Background: Cystic echinococcosis (CE) also known as hydatid disease, is a zoonotic helminthic disease
caused by infection with the larval stage of a tapeworm Echinococcus granulosus. It is an important parasite
regarding human health and is categorized into different genotypes. The present study aimed to identify different
genotypes of E. granulosus metacestode isolated from Iranian camel.
Methods: In this cross-sectional study, 54 hydatid cysts were isolated from slaughtered Iranian camels (Camelus
dromedarius) in Isfahan (33 samples) and Yazd (21 samples) province s’ laughterhouses. The DNA was extracted
from the isolated hydatid cysts and high resolution melting analysis (HRM) was performed. The curves were
confirmed by sequencing and aligning with previously deposited sequences.
Results: Based on the results of the present study, 94.4%, 3.7%, and 1.9% of the studied isolates were identified
as E. granulosus (G1), E. granulosus (G2), and E. intermedius (G6) in the two studied regions, respectively.
Moreover, 85.18% of the cysts were isolated from lung and 5.82% of them were also isolated from the liver of
Conclusion: Based on the HRM analysis of cox1 and atp6 genes, E. granulosus (G1) accounts for the most cases
of camelid cystic echinococcosis, and demonstrates camels as a source of human cystic echinococcosis.