Logo-ajcmi
Submitted: 24 May 2014
Revision: 25 Jul 2014
Accepted: 25 Aug 2014
ePublished: 20 Oct 2014
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)

Avicenna J Clin Microbiol Infect. 2014;1(3): 20612.
doi: 10.17795/ajcmi-20612
  Abstract View: 1165
  PDF Download: 694

Case Report

Acute Disseminated Encephalomyelitis Following Pneumococcal Meningitis Infection

Mohamad Mahdi Majzoobi 1, Mojgan Mamani 2, Masoud Ghiasian 3, Elham Abdoli 2*

1 Department of Infectious Diseases, Hamadan University of Medical Sciences, Hamadan, IR Iran
2 Brucella Research Center, Department of Infectious Diseases, Hamadan University of Medical Sciences, Hamadan, IR Iran
3 Department of Neurologic Diseases, Hamadan University of Medical Sciences, Hamadan, IR Iran
*Corresponding Author: Corresponding author: Elham Abdoli, Brucella Research Center, Department of Infectious Diseases, Hamadan University of Medical Sciences, Hamadan, IR Iran. Tel: +98-8138274192, Fax: +98-8138276010, Email: Eabdoli8387@yahoo.com

Abstract

Introduction: Acute disseminated encephalomyelitis (ADEM) is an acute inflammatory and demyelinating disease of the central nervous system, resulting in various neurological symptoms. Usually, the disease appears following vaccination or systemic viral infections. In rare cases, the disease appears following pneumococcal infections.

Case Presentation: The patient was a 27 year-old man who was referred to the clinic following a few days of fever and cold with consciousness deficit and right hemiplegia. Based on the analysis of cerebrospinal fluid (CSF) and diagnosis of pneumococcal meningitis, he received suitable antibiotic treatment. Despite complete return of consciousness, good general condition, and negative smear and culture of CSF, fever continued and no considerable improvement was observed in the hemiplegia. Therefore, brain magnetic resonance imaging (MRI) was performed and according to the findings, treatment was started with the diagnosis of acute disseminated encephalomyelitis. Treatment with prednisolone at first obviated the fever and after a month brought about a complete hemiplegia cure. Following the status of the patient after three months, his MRI clearly showed considerable reduction in lesions.

Discussion: There is possible occurrence of ADEM following pneumococcal meningitis. Regarding the occurrence of neurological symptoms such as visual disturbance, hemiparesis or hemiplegia following bacterial meningitis, ADEM can be considered as one of the differential diagnoses to be accompanied by MRI. Acute disseminated encephalomyelitis should be treated using suitable dose of corticosteroids.


Copyright © 2014, Hamadan University of Medical Sciences; Published by Safnek. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 1166

Your browser does not support the canvas element.


PDF Download: 694

Your browser does not support the canvas element.