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Submitted: 07 Apr 2017
Revision: 17 Nov 2017
Accepted: 21 Dec 2017
ePublished: 10 Jan 2018
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Avicenna J Clin Microbiol Infect. 2018;5(1): 64161.
doi: 10.5812/ajcmi.64161
  Abstract View: 1137
  PDF Download: 706

Case Report

Erythema Induratum of Bazin: A Rare Presentation of Tuberculosis

Seyyed Hamid Hashemi 1* ORCID logo, Mahmoud Farshchian 2, Hamidreza Ghasemi Basir 3, Maria Shirvani 4

1 Department of Infectious Diseases, Hamadan University of Medical Sciences, Hamadan, Iran
2 Department of Dermatology, Hamadan University of Medical Sciences, Hamadan, Iran
3 Department of Pathlogy, Hamadan University of Medical Sciences, Hamadan, Iran
4 Department of Infectious Diseases, Kermanshah University of Medical Sciences, Kermanshah, Iran
*Corresponding Author: Corresponding author: Dr. Seyyed Hamid Hashemi, Division of Infectious Diseases, Sina Hospital, Mirzadeh-Eshghi St, Hamadan, Iran. Tel: +98-8138274192, Fax: +98-8138276010, Email: shahashemi@yahoo.com

Abstract

Erythema induratum of bazin (EIB) is a hypersensitivity reaction to Mycobacterium tuberculosis infection. The diagnosis can be difficult because tubercle bacilli are usually not found in smears or cultures of lesions. This study reports on a case of EIB in a 13-year-old female, who presented multiple tender nodules on her lower extremities. Biopsy of the nodule revealed histopathologic changes compatible with erythema induratum. QuantiFERON test was positive. The patient received a 6-month duration of anti-tuberculosis treatment. The lesions disappeared during therapy, and no pigmentation was observed at the end of treatment. After a year of follow up, there was no recurrence of the disease.
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